2021
Bae, J., Salamon, R.J., Brandt, E.B., Paltzer, W.G., Zhang, Z., Britt, E.C., Hacker, T.A., Fan, J., Mahmoud, A.I.*. Malonate Promotes Adult Cardiomyocyte Proliferation and Heart Regeneration. Circulation, 2021 Mar 5. (*corresponding author)
2020
Salamon, R.J., Zhang, Z., Mahmoud, A.I.*. Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. Journal of Visualized Experiments, 2020 Mar 17; (157). (*corresponding author).
2019
Brandt, E.B.,Bashar, S.J., Mahmoud, A.I.*. Stimulating ideas for heart regeneration: the future of nerve-directed heart therapy. Bioelectronic Medicine, 2019 Jun 26; 5:8. (*corresponding author).
2018
Mahmoud, A.I.*and Porrello, E.R*. Upsizing Neonatal Heart Regeneration. Circulation, 2018 Dec 11;138(24):2817-2819. (*co-corresponding authors).
Mahmoud, A.I., Galdos, F.X., Dinan, K.A., Jedrychowski, M.P., Davis, J.C., Vujic, A., Rachmin, I., Shigley, C., Pancoast, J.R., Lee, S., Hollister-Lock, J., MacGillivray, C.M., Gygi, S.P., Melton, D.A., Weir, G.C., Lee, R.T. Apolipoprotein E is a Pancreatic Extracellular Factor That Maintains Mature β-Cell Gene Expression. PLOS ONE, 2018 Oct 10;13(10):e0204595.
2016
Vujic, A., Mahmoud, A.I., Lee, R.T. A breakdown in cooperativity leads to cardiac identity crisis.Cell (2016) Dec 15;167(7):1674-1676. doi: 10.1016/j.cell.2016.11.056.
Mahmoud, A.I., Lee, R.T. Adrenergic function restoration in the transplanted heart: A role for neural crest-derived cells. Cardiovasc Res (2016) Mar 1;109(3):348-9. doi: 10.1093/cvr/cvw013.
2015
Mahmoud, A.I.*, O’Meara, C.C.*, Gemberling, M., Zhao, L., Bryant, D.M., Zheng, R., Gannon, J.B., Cai, L., Choi, W., Egnaczyk, G.F., Burns, C.E., Burns, C.G., MacRae, C.A., Poss, K.D., Lee, R.T. Nerves regulate cardiomyocyte proliferation and heart regeneration. Dev Cell 2015 Aug 24;34(4):387-99. doi: 10.1016/j.devcel.2015.06.017. (* equal contributions)
2014
Puente, B.N., Kimura, W., Muralidhar, S.A., Moon, J., Amatruda, J.F., Phelps, K.L., Grinsfelder, D., Rothermel, B.A., Chen, R., Garcia, J.A., Santos, C.X., Thet, S., Mori, E., Kinter, M.T., Rindler, P.M., Zacchigna, S., Mukherjee, S., Chen, D.J., Mahmoud, A.I., Giacca, M., Rabinovitch, P.S., Aroumougame, A., Shah, A.M., Szweda, L.I., Sadek, H.A. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell (2014) Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032.
Mahmoud, A.I.*, Canseco, D.*, Xiao, F., Sadek, H.A. Cardiomyocyte cell cycle: Meis-ing something? Cell Cycle (2014);13(7):1057-8. doi: 10.4161/cc.28379. (* equal contributions)
Aurora, A.B., Porrello, E.R., Tan, W., Mahmoud, A.I., Hill, J.A., Bassel-Duby, R., Sadek, H.A., Olson, E.N. Macrophages are required for neonatal heart regeneration. J Clin Invest (2014) Mar;124(3):1382-92. doi: 10.1172/JCI72181.
Mahmoud, A.I., Porrello, E.R., Kimura, W., Olson, E.N., Sadek, H.A. Surgical models for cardiac regeneration in neonatal mice. Nat Protoc (2014) Feb;9(2):305-11. doi: 10.1038/nprot.2014.021.
2013
Muralidhar, S.A.*, Mahmoud, A.I.*, Canseco, D., Xiao, F., Sadek, H.A. Harnessing the power of dividing cardiomyocytes. Glob Cardiol Sci Pract (2013) Nov 1;2013(3):212-21. doi: 10.5339/gcsp.2013.29. (* equal contributions)
Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN. Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110.
Mahmoud, A.I.*, Kocabas, F.*, Muralidhar, S.A.*, Kimura, W., Koura, A.S., Thet, S., Porrello, E.R., Sadek, H.A. Meis1 regulates postnatal cardiomyocyte cell cycle arrest. Nature (2013) May 9;497(7448):249-253. doi: 10.1038/nature12054. (* equal contributions)
Porrello, E.R.*, Mahmoud, A.I.*, Simpson, E., Johnson, B.A., Grinsfelder, D., Canseco, D., Mammen, P.P, Rothermel, B.A., Olson, E.N., Sadek, H.A. Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proc Natl Acad Sci U S A (2013) Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. (* equal contributions)
2012
Mahmoud, A.I. and Porrello, E.R. Turning back the cardiac regenerative clock: lessons from the neonate. Trends Cardiovasc Med (2012) Jul;22(5):128-33. doi: 10.1016/j.tcm.2012.07.008.
Kocabas, F., Mahmoud, A.I., Porrello, E.R., Sosic, D., Olson, E.N., DeBerardinis, R.J., Sadek, H.A. The hypoxic epicardial and subepicardial microenvironment. J Cardiovasc Transl Res (2012) Oct;5(5):654-65.
Aurora, A.B., Mahmoud, A.I., Luo, X., Johnson, B.A., van Rooij, E., Matsuzaki, S., Humphries, K.M., Hill, J.A., Bassel-Duby, R., Sadek, H.A., Olson, E.N. MicroRNA-214 protects the heart from ischemic injury by controlling Ca2+ overload and cell death. J Clin Invest (2012) Apr;122(4):1222-32. doi: 10.1172/JCI59327.
2011
Porrello, E.R., Mahmoud, A.I., Simpson, E., Hill, J.A., Richardson, J.A., Olson, E.N., Sadek, H.A. Transient regenerative potential of the neonatal mouse heart. Science (2011) Feb 25;331(6020):1078-80. doi: 10.1126/science.1200708.
2010
Simsek, T., Kocabas, F., Zheng, J, DeBerardinis, R.J., Mahmoud, A.I., Olson, E.N., Schneider, J.W., Zhang, C.C., Sadek, H.A. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell (2010) Sep 3;7(3):380-90. doi: 10.1016/j.stem.2010.07.011.
Book Chapters
2017
Mahmoud, A.I., Lee, R.T. Past and Future of Cell Based Heart Repair. In: Cardiac Regeneration (Ieda, M., Zimmermann, W.H., editors) Springer (2017).